Last time, we discussed what parameters are tested during the quality control of drugs and dietary supplements. Today we will expand this topic a bit, discussing what types of analyses are performed in the Chemical Laboratory.
Both the drugs and dietary supplements, as well as the raw materials used in their production, must meet certain quality standards. In order to ensure the highest quality of end products, in addition to testing them themselves, we also test the quality of the raw materials before starting the manufacturing process. This control is one of the key elements to ensure the appropriate quality and safety of products. Analyses are performed here, which can be divided into the following groups.
Chemical analyses – These are based on specific chemical reactions. In this way, we can test the percentage of a given compound in the raw material and the content of an active substance in a drug, or confirm the identity of a given substance, i.e. whether the substance in the tested material is actually the one declared by the manufacturer. In the case of chemical analyses, we use, for example: colour reactions that occur for a given compound in a characteristic way, titration analyses – they allow to determine an unknown concentration of a substance in a test solution using a solution of another compound with a known concentration, reactions occurring with the precipitation of a precipitate of a specific colour, gas bubbles, etc.
Physicochemical analyses – this type of analysis uses phenomena and physical quantities to test individual materials, such as, for example, the refractive index (refractometry), differences in affinity to specific stationary and mobile phases (chromatographic techniques), absorption of light of a specific wavelength by the tested solution (spectrophotometry), pH value, etc. These methods also allow to characterize the properties of the analysed material and evaluate its quality.
If you would like to commission us to perform this type of analysis for raw materials or final products, please send an e-mail to the following address: laboratorium@labor.com.pl, b.wieclaw@labor.com.pl or r.kowalczyk@labor.com.pl to determine details of the offer.
We look forward to working with you!
AUTHOR: mgr inż. Katarzyna Trębicka