{"id":1047,"date":"2020-10-10T13:23:05","date_gmt":"2020-10-10T13:23:05","guid":{"rendered":"https:\/\/www.labor.com.pl\/?p=1047"},"modified":"2021-06-23T09:12:21","modified_gmt":"2021-06-23T09:12:21","slug":"kilka-slow-o-odpornosci","status":"publish","type":"post","link":"https:\/\/www.labor.com.pl\/en\/kilka-slow-o-odpornosci\/","title":{"rendered":"A few words about immunity"},"content":{"rendered":"<p><em>Summary<\/em><\/p>\n<p><em>Immunity is a state of the organism in which it is resistant to various unfavorable factors, such as food<\/em><br \/>\n<em>deficiency and toxins. We divide it into specific and non-specific immunity, depending on the<\/em><br \/>\n<em>specificity of its action. It can be weakened by various factors, including by sleep deprivation and<\/em><br \/>\n<em>smoking. Examples of immune-boosting elements include an appropriate diet and physical activity<\/em><br \/>\n<em>adapted to the body&#8217;s capabilities. Preparations containing the extract of echinacea and vitamin C of<\/em><br \/>\n<em>natural origin also have a positive effect on its support.<\/em><\/p>\n<p>Echinacea (Echinacea purpurea) extract is a commonly known and used agent that strengthens the<br \/>\nbody&#8217;s immunity. Echinacea monograph, published by the EMA, as an indication for the<br \/>\nadministration of echinacea extract, mentions its use in prevention and treatment. Recommended<br \/>\npreparations containing purple coneflower extract, vitamin C from natural sources and zinc are, for<br \/>\nexample, Echimunn C, containing vitamin C from rosehip extract (Rosa canina) and purple coneflower<br \/>\nherb extract (Echinacea purpurea), containing 4% polyphenols and also zinc.<\/p>\n<p>A similar product is Echimunn tablets, which includes the extract of Echinacea purpurea herb,<br \/>\ncontaining 4% polyphenols, which corresponds to 1000 mg of dried herb.<\/p>\n<p>What is immunity?<br \/>\nImmunity &#8211; the state of the organism&#8217;s resistance to adverse external factors, such as lack of water,<br \/>\nlack of food, the presence of toxins, parasites, pathogenic microorganisms. In biology, immunity is<br \/>\nunderstood as maintaining the equilibrium state of multicellular organisms between the efficient<br \/>\nmechanisms of biological defense against infection and disease states and the maintenance of the<br \/>\nstate of tolerance, which prevents allergies and autoimmune diseases. A special type of immunity is<br \/>\nimmunological immunity [1].<\/p>\n<p>How does the human immune system work?<br \/>\nOrganism is protected against infections, as well as the adverse effects of harmful substances from<br \/>\nthe environment, by two protective systems:<\/p>\n<p>1) Non-specific immunity<br \/>\nIt is a system of barriers that prevent harmful factors from entering into the body. Non-specific<br \/>\nimmunity is based on physical, chemical and cellular barriers.<\/p>\n<p>? Physical barriers that create mechanical protection are the main obstacles that pathogens<br \/>\nencounter when trying to enter our body. The body is protected against the penetration of<br \/>\nenvironmental factors by the skin and mucous membranes of the respiratory and urinary tract and<br \/>\nthe digestive tract. The body also gets rid of pathogens through protective reflexes, such as sneezing,<br \/>\ncoughing or vomiting.<br \/>\n? Chemical barriers include secretions such as sweat and tallow, hydrochloric acid in the stomach, and<br \/>\nsubstances in tears and saliva that kill bacteria and viruses.<br \/>\n? The cell barrier is the defence cells &#8211; leukocytes and macrophages. They are activated when<br \/>\npathogens manage to overcome physical and chemical barriers and penetrate the body&#8217;s tissues.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter size-large wp-image-1050\" src=\"https:\/\/www.labor.com.pl \/wp-content\/uploads\/2020\/10\/viktor-forgacs-FcDqdJUM6B4-unsplash-1024x576.jpg\" alt=\"\" width=\"1024\" height=\"576\" srcset=\"https:\/\/www.labor.com.pl\/wp-content\/uploads\/2020\/10\/viktor-forgacs-FcDqdJUM6B4-unsplash-1024x576.jpg 1024w, https:\/\/www.labor.com.pl\/wp-content\/uploads\/2020\/10\/viktor-forgacs-FcDqdJUM6B4-unsplash-300x169.jpg 300w, https:\/\/www.labor.com.pl\/wp-content\/uploads\/2020\/10\/viktor-forgacs-FcDqdJUM6B4-unsplash-768x432.jpg 768w, https:\/\/www.labor.com.pl\/wp-content\/uploads\/2020\/10\/viktor-forgacs-FcDqdJUM6B4-unsplash-1080x608.jpg 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<p>2) Specific immunity<\/p>\n<p>? When pathogens enter the body&#8217;s tissues and begin to spread there, the immune system,<br \/>\nresponsible for the generation of specific immunity, intervenes. It recognizes and then neutralizes<br \/>\nspecific microorganisms. There is an increase in the activity of leukocytes, macrophages and T and B<br \/>\nlymphocytes (white blood cells).<br \/>\n? Viruses and bacteria have, on their surface, antigens which are specific types of proteins.<br \/>\nLymphocytes B present in the blood produce appropriate antibodies that match the shape of a<br \/>\nspecific antigen. This mechanism is called the induced fit model. From the moment of contact with a<br \/>\nforeign antigen, the number of antibodies in the bloodstream increases rapidly.<br \/>\n? Viruses and bacteria have antigens, which are specific types of proteins, on their surface. B<br \/>\nlymphocytes present in the blood produce appropriate antibodies that match the shape of a specific<br \/>\nantigen. This mechanism is called the induced fit model. From the moment of contact with a foreign<br \/>\nantigen, the number of antibodies in the bloodstream increases rapidly. The antibodies surround the<br \/>\nidentified pathogen. It is a signal for macrophages, cells of the immune system capable of devouring<br \/>\nforeign bodies, to destroy such indicated objects. The specificity of antibodies means that a certain<br \/>\ntype of antibodies is capable of being destroyed only for the antigen to which they are matched. After<br \/>\nfighting foreign bodies, a certain number of lymphocytes remain in the bloodstream &#8211; memory cells<br \/>\nthat, in the event of another infection, are able to multiply rapidly, produce specific antibodies and<br \/>\nstart the fight against recognized, already known pathogens, preventing the development of another<br \/>\ninfection. T lymphocytes also destroy damaged cells of the body&#8217;s own, e.g. defective cells or infected<br \/>\nwith viruses.<\/p>\n<p>What does weaken our immunity?<br \/>\nThere are many factors that can weaken our immunity. The most important of them include:<\/p>\n<p>? Cigarette smoking &#8211; there are over 4,000 toxic substances in tobacco smoke, often also carcinogenic.<br \/>\n? Abuse of alcohol, which penetrates quickly into the blood and lymphatic system, kills in them<br \/>\nimmune cells,<br \/>\n? Inadequate nutrition &#8211; a diet containing, for example, an insufficient amount of vitamins and trace<br \/>\nelements, while at the same time too high in fats and calories,<br \/>\n? Irregular lifestyle &#8211; has a negative impact on our physical condition, which also means weakening<br \/>\nthe functioning of our immune system,<br \/>\n? Sleep deficit &#8211; the state of fatigue weakens the body, and thus reduces our immunity,<br \/>\n? Emotional stress &#8211; the immune system closely interacts with the central nervous system, and its<br \/>\ndisturbances have a negative effect on the immune system.<br \/>\nHow can we improve immunity?<br \/>\nThe basic factors that increase our immunity are:<br \/>\n? Physical activity &#8211; we should exercise for 30 &#8211; 60 minutes, at least 3 times a week. Walking, jogging,<br \/>\nswimming, cycling and outdoor exercise games are especially recommended. However, it should be<br \/>\nremembered that the intensity of exercise should be adjusted to the age and general physical<br \/>\ncapacity. It should be increased gradually.<br \/>\n? Regular lifestyle, avoiding stress, getting enough sleep.?<br \/>\n? Quenching &#8211; frequent outdoor activities, avoiding overheating (but it does not mean overcooling<br \/>\nand getting wet!). It is the best to start hardening the body in the summer season.<br \/>\n? A proper diet that includes age and gender-appropriate amounts of nutrients such as proteins,<br \/>\ncarbohydrates and fats; it should also cover the daily requirement for micronutrients, e.g. zinc, as well<br \/>\nas basic vitamins (e.g. vitamin C, B vitamins and vitamins A, D3 and E contained in fats). Doctors<br \/>\nespecially emphasize the role of ascorbic acid (vitamin C), which reduces the permeability of<br \/>\ncapillaries and strengthens their walls, which increases the resistance of mucous membranes to<br \/>\ninfections. Vitamin C from natural sources, such as rosehips, is especially valuable.<\/p>\n<p>Echinacea (Echinacea purpurea) extract is a commonly known and used agent that strengthens the<br \/>\nbody&#8217;s immunity.<br \/>\nEchinacea monograph, published by the European Medicines Agency [2], mentions its use in the<br \/>\nprevention and treatment of colds as an indication for the administration of echinacea extract.<br \/>\nHowever, therapy should not last longer than 10 days.<\/p>\n<p>Recommended products containing purple echinacea extract and vitamin C from natural sources and<br \/>\nzinc are, for example, Echimunn C with vitamin C derived from rosehip extract (Rosa canina with an<br \/>\nextract of echinacea herb (Echinacea purpurea), containing 4% polyphenols and zinc.<br \/>\nA similar preparation is Echimunn tablets, which includes the extract of Echinacea purpurea herb,<br \/>\ncontaining 4% polyphenols, corresponding to 1000 mg of dried herb.<\/p>\n<p>&nbsp;<\/p>\n<p><em>AUTHOR: Dr n. farm. Andrzej Tarasiuk<\/em><\/p>\n<p>Bibliography:<br \/>\n1. Wikipedia ( https:\/\/pl.wikipedia.org\/wiki\/Odporno%C5%9B%C4%87 ).<br \/>\n2. 24 November 2015 EMA\/HMPC\/48704\/2014 Corr 1 Committee on Herbal Medicinal<br \/>\nProducts (HMPC) European Union herbal monograph on Echinacea purpurea (L.)<br \/>\nMoench, herba recens [ https:\/\/www.ema.europa.eu\/en\/documents\/herbal-<br \/>\nmonograph\/final-european-union-herbal-monograph-echinacea-purpurea-l-moench-<br \/>\nherba-recens_en.pdf ]?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Summary Immunity is a state of the organism in which it is resistant to various unfavorable factors, such as food deficiency and toxins. We divide it into specific and non-specific immunity, depending on the specificity of its action. It can be weakened by various factors, including by sleep deprivation and smoking. Examples of immune-boosting elements [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":605,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":""},"categories":[112,62],"tags":[50],"_links":{"self":[{"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/posts\/1047"}],"collection":[{"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/comments?post=1047"}],"version-history":[{"count":9,"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/posts\/1047\/revisions"}],"predecessor-version":[{"id":2934,"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/posts\/1047\/revisions\/2934"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/media\/605"}],"wp:attachment":[{"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/media?parent=1047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/categories?post=1047"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.labor.com.pl\/en\/wp-json\/wp\/v2\/tags?post=1047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}